In the hospital, Pampers Swaddlers will (probably) be the first diaper to hit your baby’s bottom. I am very happy with the performance of Pampers; they are soft, fit well, and contain leaks. Pampers Swaddlers are incredibly soft and have an umbilical cord notch for newbies. They also have a line that changes color to indicate wetness (Swaddlers also come in a Sensitive version).
If you’re spending that much, and you’re in the market for something with a few more bells and whistles, I also like the Hatch Baby Grow ($129), an integrated baby scale and changing pad in one. The scale allows you to track weight gain, milk intake and other such things that are typically only ascertained by a visit to a pediatrician’s office. I would especially recommend this for parents who are the “need to know” type (those who like to have lots of data) or if you have any reason to expect a preemie (you are pregnant with multiples, high risk, etc.).